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ADOConnection._Execute(INSERT INTO controlled_vocabs (symbolic, assoc_type, assoc_id) VALUES ('submissionKeyword', 1048585, 158)) % line 1032, file: adodb.inc.php
ADOConnection.Execute(INSERT INTO controlled_vocabs (symbolic, assoc_type, assoc_id) VALUES ('submissionKeyword', 1048585, 158), Array[1]) % line 228, file: DAO.inc.php
DAO.update(INSERT INTO controlled_vocabs (symbolic, assoc_type, assoc_id) VALUES (?, ?, ?), Array[3], true, false) % line 99, file: ControlledVocabDAO.inc.php
ControlledVocabDAO.insertObject(Object:ControlledVocab, false) % line 60, file: ControlledVocabDAO.inc.php
ControlledVocabDAO._build(submissionKeyword, 1048585, 158) % line 30, file: SubmissionKeywordDAO.inc.php
(mysqli): SELECT * FROM controlled_vocabs WHERE symbolic = 'submissionKeyword' AND assoc_type = 1048585 AND assoc_id = 158
(mysqli): SELECT cve.* FROM controlled_vocab_entries cve WHERE cve.controlled_vocab_id = 710 ORDER BY seq
(mysqli): SELECT * FROM controlled_vocab_entry_settings WHERE controlled_vocab_entry_id = '491'
(mysqli): SELECT ps.*,
s.*,
COALESCE(stl.setting_value, stpl.setting_value) AS section_title,
COALESCE(sal.setting_value, sapl.setting_value) AS section_abbrev
FROM published_submissions ps
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WHERE sst.setting_name = 'pub-id::publisher-id' AND sst.setting_value = '158' ORDER BY ps.issue_id, s.submission_id
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s.*,
COALESCE(stl.setting_value, stpl.setting_value) AS section_title,
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WHERE s.submission_id = 158
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LEFT JOIN submission_files sf ON (g.file_id = sf.file_id)
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SELECT iss.subscription_id
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OR st.format = 17)
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FROM authors a
JOIN user_groups ug ON (a.user_group_id=ug.user_group_id)
JOIN submissions s ON (s.submission_id = a.submission_id)
WHERE a.submission_id = 158 ORDER BY seq
(mysqli): SELECT * FROM author_settings WHERE author_id = '278'
(mysqli): SELECT * FROM author_settings WHERE author_id = '279'
(mysqli): SELECT * FROM author_settings WHERE author_id = '280'
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JOIN user_groups ug ON (a.user_group_id=ug.user_group_id)
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WHERE a.submission_id = 158 AND a.include_in_browse = 1 ORDER BY seq
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(mysqli): INSERT INTO controlled_vocabs
(symbolic, assoc_type, assoc_id)
VALUES
('submissionKeyword', 1048585, 158)
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(symbolic, assoc_type, assoc_id)
VALUES
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DAO.update(INSERT INTO controlled_vocabs (symbolic, assoc_type, assoc_id) VALUES (?, ?, ?), Array[3], true, false) % line 99, file: ControlledVocabDAO.inc.php
ControlledVocabDAO.insertObject(Object:ControlledVocab, false) % line 60, file: ControlledVocabDAO.inc.php
ControlledVocabDAO._build(submissionKeyword, 1048585, 158) % line 30, file: SubmissionKeywordDAO.inc.php
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(mysqli): SELECT * FROM author_settings WHERE author_id = '280'
(mysqli): INSERT INTO controlled_vocabs
(symbolic, assoc_type, assoc_id)
VALUES
('submissionKeyword', 1048585, 158)
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(symbolic, assoc_type, assoc_id)
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ADOConnection._Execute(INSERT INTO controlled_vocabs (symbolic, assoc_type, assoc_id) VALUES ('submissionKeyword', 1048585, 158)) % line 1032, file: adodb.inc.php
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DAO.update(INSERT INTO controlled_vocabs (symbolic, assoc_type, assoc_id) VALUES (?, ?, ?), Array[3], true, false) % line 99, file: ControlledVocabDAO.inc.php
ControlledVocabDAO.insertObject(Object:ControlledVocab, false) % line 60, file: ControlledVocabDAO.inc.php
ControlledVocabDAO._build(submissionKeyword, 1048585, 158) % line 30, file: SubmissionKeywordDAO.inc.php
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(mysqli): SELECT cve.* FROM controlled_vocab_entries cve WHERE cve.controlled_vocab_id = 710 ORDER BY seq
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EFFECTS OF PROBIOTIC SACCHAROMYCES BOULARDII AND CO-TRIMOXAZOLE ON SOME HAEMATOLOGICAL PARAMETERS IN ADULT WISTAR RATS
| African Journal of Health, Safety and Environment
EFFECTS OF PROBIOTIC SACCHAROMYCES BOULARDII AND CO-TRIMOXAZOLE ON SOME HAEMATOLOGICAL PARAMETERS IN ADULT WISTAR RATS
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WHERE a.submission_id = 158 ORDER BY seq
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P. A. Obazelu
Department of Medical Laboratory Science, School of Basic Medical Sciences, University of Benin, Benin City, Nigeria
I. A. Aruomaren
Department of Medical Laboratory Science, School of Basic Medical Sciences, University of Benin, Benin City, Nigeria
C. C. Nwangwu
Department of Medical Laboratory Science, School of Basic Medical Sciences, University of Benin, Benin City, Nigeria
Keywords:
Saccharomyces boulardii, co-trimoxazole, packed cell volume, total white blood cell count, platelet count, mean platelet volume
Abstract
Saccharomyces boulardii is a probiotic yeast used as a nutritional supplement. Co-trimoxazole, is a broad-spectrum antimicrobial agent used in the prophylaxis and treatment of infections.The goal of this study was to evaluate the individual and interactive effects of probiotic Saccharomyces boulardii and co-trimoxazole on some haematological parameters in albino rats. Thirty (30) albino Wistar rats weighing 150-200g were divided into five groups; Basal, A, B, C, and D, with six animals in each group. Group A (control) was given a normal rat pellet (standardized feed) and clean water (pH 6.5- 8.5). Group B was administered 5.5mg/kg body weight of the commercial probiotics (Saccharomyces boulardii). Group C was administered 4.4mg/kg body weight of co-trimoxazole. Group D was administered 5.5mg/kg body weight of the commercial probiotics and 4.4mg/kg body weight of co-trimoxazole. All administrations were done using a gavage tube for 15 days. Blood samples were collected for analysis on days 0, 5 and 15. The results showed that Saccharomyces boulardii caused a significant increase (P<0.05) in total white blood cell count and packed cell volume of the treated groups at day 5. On day 15, the total white blood cell count (10.67±0.66), packed cell volume (43.23±0.47), platelet count (932±38.89) and mean platelet volume (8.53±0.38) showed a significant increase (P<0.05) in the probiotic group. The co-trimoxazole group showed a significant reduction (P<0.05) in the packed cell volume and total white blood cell count. This study shows that Saccharomyces boulardii has a positive effect on the haematological profile of the test animals.
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(mysqli): SELECT setting_name, setting_value, setting_type FROM plugin_settings WHERE plugin_name = 'usagestatsplugin' AND context_id = 1
(mysqli): SELECT a.*, ug.show_title, s.locale
FROM authors a
JOIN user_groups ug ON (a.user_group_id=ug.user_group_id)
JOIN submissions s ON (s.submission_id = a.submission_id)
WHERE a.submission_id = 158 ORDER BY seq
(mysqli): SELECT * FROM author_settings WHERE author_id = '278'
(mysqli): SELECT * FROM author_settings WHERE author_id = '279'
(mysqli): SELECT * FROM author_settings WHERE author_id = '280'
Obazelu, P. A., Aruomaren, I. A., & Nwangwu, C. C. (2021). EFFECTS OF PROBIOTIC SACCHAROMYCES BOULARDII AND CO-TRIMOXAZOLE ON SOME HAEMATOLOGICAL PARAMETERS IN ADULT WISTAR RATS. African Journal of Health, Safety and Environment, 2(2), 55 - 62. https://doi.org/10.52417/ajhse.v2i2.158
